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Search Results for " kdm5 inhibitor "

18

Compounds

Cat No. Product Name Synonyms Targets
T15648 KDM5-C70 Histone Demethylase
KDM5-C70 is an ethyl ester derivative of KDM5-C49. KDM5-C70 is an effective, cell-permeable, and pan-KDM5 histone demethylase inhibitor. KDM5-C70 has an antiproliferative effect in myeloma cells, inducing a genome-wide e...
T15649 KDM5-IN-1 Histone Demethylase
KDM5-IN-1 is an effective and selective inhibitor of KDM5 with an IC50 of 15.1 nM.
T3576 CPI-455 analogue CPI-455 analogue Others
CPI-455 analogue (CPI-455 analogue) is an analogue of CPI-455 which is a KDM5 inhibitor.
T3552 CPI-455 CPI-455 HCl Histone Demethylase
CPI-455 is a specific KDM5 inhibitor.
T27723L KDM5-C49 HCl KDM5-C49 HCl(1596348-16-1 Free base),KDOAM-20 hydrochloride Histone Demethylase
KDM5-C49 HCl (KDOAM-20 hydrochloride) is a potent and selective inhibitor of KDM5 demethylase. KDM5-C49 HCL(1596348-16-1 Free base) is a candidate compound for the treatment of cancer.
T5484 GSK467 Histone Demethylase , Histone Methyltransferase
GSK467 is a potent and selective inhibitor of KDM5 (JARID1)(Ki : 10 nM).
T39989L JQKD82 trihydrochloride Histone Demethylase
JQKD82 trihydrochloride, a cell-permeable and selective inhibitor of KDM5, enhances H3K4me3 levels and is utilized in multiple myeloma research.
T15650 KDM5A-IN-1 Histone Demethylase
KDM5A-IN-1 is an orally available, potent and selective inhibitor of the pan-histidine lysine demethylase 5 KDM5, inhibiting KDM5A, KDM5B, and KDM5C with IC50 values of 45 nM, 56 nM, and 55 nM, respectively.KDM5A-IN-1 in...
T39989 JQKD82 JADA82,PCK82,JQKD82 Histone Demethylase
JQKD82 is a selective inhibitor of KDM5 and increases H3K4me3. JQKD82 can be used in studies about the treatment of multiple myeloma.
T27723 KDM5-C49 KDM5C49
KDM5-C49 is a potent and selective inhibitor of KDM5, which regulates cell proliferation and stem cell self-renewal and differentiation.
T27070 CPI-4203 CPI4203,CPI 4203
CPI-4203 is a selective inhibitor of KDM5 demethylases.
T73849 KDM5-C49 hydrochloride
KDM5-C49 (KDOAM-20) hydrochloride is a potent, selective inhibitor of the KDM5 family of demethylases, demonstrating IC50 values of 40 nM for KDM5A, 160 nM for KDM5B, and 100 nM for KDM5C, respectively. This compound is ...
T11749 KDM4-IN-2 Glucokinase
KDM4-IN-2 is a potent and selective KDM4/KDM5 dual inhibitor with Kis of 4 and 7 nM for KDM4A and KDM5B, respectively.
T11750 KDOAM-25 citrate Others
KDOAM-25 citrate is a potent and highly selective histone lysine demethylases 5 (KDM5) inhibitor with IC 50 s of 71 nM, 19 nM, 69 nM, 69 nM for KDM5A, KDM5B, KDM5C, KDM5D, respectively. Multiple myeloma MM1S cells treate...
T11751 KDOAM-25 Antibacterial
KDOAM-25, a potent and highly selective inhibitor of histone lysine demethylases 5 (KDM5) with IC50 values of 71 nM for KDM5A, 19 nM for KDM5B, 69 nM for KDM5C, and 69 nM for KDM5D, enhances global H3K4 methylation at tr...
T22299 CPI-455 HCl Histone Demethylase
CPI-455 is a specific KDM5 inhibitor with IC50 value of 10 ± 1 nM for full-length KDM5A in enzymatic assays, elevating global levels of H3K4 trimethylation (H3K4me3) and decreased the number of DTPs in multiple cancer c...
T62166 KDOAM-25 trihydrochloride
KDOAM-25 trihydrochloride is a potent and highly selective inhibitor of histone lysine demethylase 5 (KDM5), acting on KDM5A (IC50: 71 nM), KDM5B (IC50: 19 nM), KDM5C (IC50: 69 nM), KDM5D (IC50: 69 nM). KDOAM-25 trihydro...
T11750L KDOAM-25 trihydrochloride (2230731-99-2 free base) KDOAM-25 trihydrochloride Others
KDOAM-25 trihydrochloride increases global H3K4 methylation at transcriptional start sites and impairs proliferation in multiple myeloma MM1S cells. KDOAM-25 trihydrochloride is a potent and highly selective histone lysi...
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