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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15648 | KDM5-C70 | Histone Demethylase | |
KDM5-C70 is an ethyl ester derivative of KDM5-C49. KDM5-C70 is an effective, cell-permeable, and pan-KDM5 histone demethylase inhibitor. KDM5-C70 has an antiproliferative effect in myeloma cells, inducing a genome-wide e... | |||
T15649 | KDM5-IN-1 | Histone Demethylase | |
KDM5-IN-1 is an effective and selective inhibitor of KDM5 with an IC50 of 15.1 nM. | |||
T3576 | CPI-455 analogue | CPI-455 analogue | Others |
CPI-455 analogue (CPI-455 analogue) is an analogue of CPI-455 which is a KDM5 inhibitor. | |||
T3552 | CPI-455 | CPI-455 HCl | Histone Demethylase |
CPI-455 is a specific KDM5 inhibitor. | |||
T27723L | KDM5-C49 HCl | KDM5-C49 HCl(1596348-16-1 Free base),KDOAM-20 hydrochloride | Histone Demethylase |
KDM5-C49 HCl (KDOAM-20 hydrochloride) is a potent and selective inhibitor of KDM5 demethylase. KDM5-C49 HCL(1596348-16-1 Free base) is a candidate compound for the treatment of cancer. | |||
T5484 | GSK467 | Histone Demethylase , Histone Methyltransferase | |
GSK467 is a potent and selective inhibitor of KDM5 (JARID1)(Ki : 10 nM). | |||
T39989L | JQKD82 trihydrochloride | Histone Demethylase | |
JQKD82 trihydrochloride, a cell-permeable and selective inhibitor of KDM5, enhances H3K4me3 levels and is utilized in multiple myeloma research. | |||
T15650 | KDM5A-IN-1 | Histone Demethylase | |
KDM5A-IN-1 is an orally available, potent and selective inhibitor of the pan-histidine lysine demethylase 5 KDM5, inhibiting KDM5A, KDM5B, and KDM5C with IC50 values of 45 nM, 56 nM, and 55 nM, respectively.KDM5A-IN-1 in... | |||
T39989 | JQKD82 | JADA82,PCK82,JQKD82 | Histone Demethylase |
JQKD82 is a selective inhibitor of KDM5 and increases H3K4me3. JQKD82 can be used in studies about the treatment of multiple myeloma. | |||
T27723 | KDM5-C49 | KDM5C49 | |
KDM5-C49 is a potent and selective inhibitor of KDM5, which regulates cell proliferation and stem cell self-renewal and differentiation. | |||
T27070 | CPI-4203 | CPI4203,CPI 4203 | |
CPI-4203 is a selective inhibitor of KDM5 demethylases. | |||
T73849 | KDM5-C49 hydrochloride | ||
KDM5-C49 (KDOAM-20) hydrochloride is a potent, selective inhibitor of the KDM5 family of demethylases, demonstrating IC50 values of 40 nM for KDM5A, 160 nM for KDM5B, and 100 nM for KDM5C, respectively. This compound is ... | |||
T11749 | KDM4-IN-2 | Glucokinase | |
KDM4-IN-2 is a potent and selective KDM4/KDM5 dual inhibitor with Kis of 4 and 7 nM for KDM4A and KDM5B, respectively. | |||
T11750 | KDOAM-25 citrate | Others | |
KDOAM-25 citrate is a potent and highly selective histone lysine demethylases 5 (KDM5) inhibitor with IC 50 s of 71 nM, 19 nM, 69 nM, 69 nM for KDM5A, KDM5B, KDM5C, KDM5D, respectively. Multiple myeloma MM1S cells treate... | |||
T11751 | KDOAM-25 | Antibacterial | |
KDOAM-25, a potent and highly selective inhibitor of histone lysine demethylases 5 (KDM5) with IC50 values of 71 nM for KDM5A, 19 nM for KDM5B, 69 nM for KDM5C, and 69 nM for KDM5D, enhances global H3K4 methylation at tr... | |||
T22299 | CPI-455 HCl | Histone Demethylase | |
CPI-455 is a specific KDM5 inhibitor with IC50 value of 10 ± 1 nM for full-length KDM5A in enzymatic assays, elevating global levels of H3K4 trimethylation (H3K4me3) and decreased the number of DTPs in multiple cancer c... | |||
T62166 | KDOAM-25 trihydrochloride | ||
KDOAM-25 trihydrochloride is a potent and highly selective inhibitor of histone lysine demethylase 5 (KDM5), acting on KDM5A (IC50: 71 nM), KDM5B (IC50: 19 nM), KDM5C (IC50: 69 nM), KDM5D (IC50: 69 nM). KDOAM-25 trihydro... | |||
T11750L | KDOAM-25 trihydrochloride (2230731-99-2 free base) | KDOAM-25 trihydrochloride | Others |
KDOAM-25 trihydrochloride increases global H3K4 methylation at transcriptional start sites and impairs proliferation in multiple myeloma MM1S cells. KDOAM-25 trihydrochloride is a potent and highly selective histone lysi... |